Peter Kioso and Alex Jones are both major doubts to feature in the game against Peterborough United on Friday night, kick-off 7.45pm.
Jon Brady is already definitely without a number of players including Mickel Miller, Jack Sowerby, Benny Ashley-Seal and Steve Arnold.
“Alex is struggling with his Achilles,” he said.
“We’ve tried to manage him and look after him but he’s not played for a year and a half.
“He had a very good half an hour when he came on against Bristol Rivers but I’d say Alex and Peter are both huge doubts for Friday but we will keep monitoring them.
“We have got injuries and the same players are having a massive output every single week.
"The squad is stretched but the players are giving it absolutely everything they’ve got and that is all that I or anyone else can ask for.”